Sivelestat sodium salt

Catalog No.: A14073

Neutrophil elastase inhibitor

Sivelestat sodium salt

Sivelestat sodium salt Chemical Structure

CAS NO. 150374-95-1

Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. It inhibits NF-kB activation and LTB4-induced neutrophil transmigration in vitro.

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10 mg
$70.00
25 mg
$140.00
50 mg
$240.00
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Biological Activity

Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. It inhibits NF-kB activation and LTB4-induced neutrophil transmigration in vitro.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.91 mL 109.54 mL 219.09 mL
0.5 mM 4.38 mL 21.91 mL 43.82 mL
1 mM 2.19 mL 10.95 mL 21.91 mL
5 mM 0.44 mL 2.19 mL 4.38 mL

*The above data is based on the productmolecular weight 456.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14073
Actions Inhibitor
M. Wt 456.44
Formula C20H21N2NaO7S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 150374-95-1
Synonyms ONO-5046
SMILES CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].[Na+]

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