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SMI-4a

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Pim Inhibitor

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Catalog No. A11945

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SMI-4a 10mg A11945-10

Regular Price: $65.00

Special Price: $52.00

SMI-4a 25mg A11945-25

Regular Price: $140.00

Special Price: $112.00

SMI-4a 50mg A11945-50

Regular Price: $260.00

Special Price: $208.00

SMI-4a 100mg A11945-100

Regular Price: $500.00

Special Price: $400.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SIM-4a is a Pim kinase inhibitor that blocks mTORC1 activity via activation of AMPK. Mostly potent to Pim-2, does not significantly inhibit any other serine/threonine- or tyrosine-kinases.

SMI-4a

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Chemical Information

Catalog Num A11945
Actions Inhibitor
M. Wt 273.2
Formula C11H6F3NO2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 327033-36-3
Synonyms SMI4a
SMILES code C1=CC(=CC(=C1)C(F)(F)F)/C=C\2/C(=O)NC(=O)S2
Chemical Name 5-?[[3-?(trifluoromethyl)phenyl]methylene]-?2,?4-?thiazolidinedione

Biological Activity

Description
SIM-4a is a Pim kinase inhibitor that blocks mTORC1 activity via activation of AMPK. Mostly potent to Pim-2, does not significantly inhibit any other serine/threonine- or tyrosine-kinases.

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