1,2-Bis(2-iodoethoxy)ethane is a PEG-based linker designed for use in PROTAC (Proteolysis Targeting Chimeras) applications. This compound facilitates the development of potent BTK (Bruton's tyrosine kinase) degraders, such as MT802 and SJF620, which exhibit degradation capabilities with DC50 values of 1 nM and 7.9 nM, respectively. Its application extends to advancing research in targeted protein degradation, offering a valuable tool for studies in cancer and autoimmune diseases.
1,2-Bis(2-iodoethoxy)ethane is a PEG-based linker designed for use in PROTAC (Proteolysis Targeting Chimeras) applications. This compound facilitates the development of potent BTK (Bruton's tyrosine kinase) degraders, such as MT802 and SJF620, which exhibit degradation capabilities with DC50 values of 1 nM and 7.9 nM, respectively. Its application extends to advancing research in targeted protein degradation, offering a valuable tool for studies in cancer and autoimmune diseases.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
