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|Storage||at -20°C 3 years Powder|
|Chemical Name||Pyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one, 9-bromo-7,12-dihydro-|
|1-Azakenpaullone is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25.|
|Solubility (25°C)*||In vitro||DMSO||66 mg/mL (201.12 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||<1 mg/mL (<1 mM)|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||30.47 mL||152.36 mL||304.73mL|
|0.5 mM||6.09 mL||30.47 mL||60.95 mL|
|1 mM||3.05 mL||15.24 mL||30.47 mL|
|5 mM||0.61 mL||3.05 mL||6.09 mL|
*The above data is based on the productmolecular weight 328.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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