1'-(tert-Butoxy)carbonyl-1,3'-biazetidine-3-carboxylic acid

Catalog No.: A84226
PROTAC Linker
1'-[(tert-Butoxy)carbonyl]-[1,3'-biazetidine]-3-carboxylic acid serves as a PROTAC linker essential for the development of targeted protein degradation strategies. By facilitating the assembly of E3 ligase and target proteins, this compound enhances the efficacy of PROTACs in modulating cellular protein levels. Its unique structural properties make it a valuable tool for chemical biology research focused on targeted therapies.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description1'-[(tert-Butoxy)carbonyl]-[1,3'-biazetidine]-3-carboxylic acid serves as a PROTAC linker essential for the development of targeted protein degradation strategies. By facilitating the assembly of E3 ligase and target proteins, this compound enhances the efficacy of PROTACs in modulating cellular protein levels. Its unique structural properties make it a valuable tool for chemical biology research focused on targeted therapies.
Product Information
Catalog NumA84226
FormulaC12H20N2O4
Molecular Weight256.30
CAS Number889952-23-2
SMILESO=C(OC(C)(C)C)N1CC(N2CC(C(=O)O)C2)C1
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