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10-Deacetyltaxol

Catalog No.: A54826
Taxane Derivative
10-Deacetyltaxol, a taxane derivative, primarily targets tubulin polymerization in microtubule dynamics. It effectively promotes the assembly of tubulin and inhibits depolymerization induced by cold conditions or calcium ions in vitro. This compound displays significant cytotoxicity against human glial and neuroblastoma cell lines, making it valuable for research in cancer biology and therapeutics.
10-Deacetyltaxol 78432-77-6 Taxane Derivative
Grouped product items
Size Price Stock Qty
5mg
$25.00
In stock
10mg
$35.00
In stock
20mg
$50.00
In stock
25mg
$55.00
In stock
50mg
$80.00
In stock
100mg
$110.00
In stock
200mg
$155.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description10-Deacetyltaxol, a taxane derivative, primarily targets tubulin polymerization in microtubule dynamics. It effectively promotes the assembly of tubulin and inhibits depolymerization induced by cold conditions or calcium ions in vitro. This compound displays significant cytotoxicity against human glial and neuroblastoma cell lines, making it valuable for research in cancer biology and therapeutics.
Product Information
Catalog NumA54826
FormulaC45H49NO13
Molecular Weight811.87
CAS Number78432-77-6
SMILESCC(O[C@]12[C@@]([C@]3([C@@H](O)C[C@@]1([H])OC2)C)([H])[C@@H]([C@]4(C(C)(C([C@@H](O)C3=O)=C(C)[C@@H](OC([C@H](O)[C@H](C5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)C4)C)O)OC(C7=CC=CC=C7)=O)=O
Synonyms10-Deacetylpaclitaxel
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Cytoskeleton > Microtubule/Tubulin