10-DEBC HCl

Catalog No.: A13590

AKT/PKB inhibitor‎

10-DEBC HCl

10-DEBC HCl Chemical Structure

CAS NO. 925681-41-0

10-DEBC HCl is a selective inhibitor of Akt/PKB. It inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein.

Availability: In stock

Package Price Qty
10 mg
$100.00
25 mg
$200.00
50 mg
$320.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

10-DEBC HCl is a selective inhibitor of Akt/PKB. It inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.23 mL 131.13 mL 262.26 mL
0.5 mM 5.25 mL 26.23 mL 52.45 mL
1 mM 2.62 mL 13.11 mL 26.23 mL
5 mM 0.52 mL 2.62 mL 5.25 mL

*The above data is based on the productmolecular weight 381.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A13590
Actions Inhibitor
M. Wt 381.3
Formula C20H25ClN2OHCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 925681-41-0
Synonyms Akt Inhibitor X
SMILES CCN(CC)CCCCN1C2=CC=CC=C2OC3=C1C=C(C=C3)Cl.Cl

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