Total item
Cart Subtotal
$0.00 Biological Activity
10-DEBC HCl is a selective inhibitor of Akt/PKB. It inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.23 mL | 131.13 mL | 262.26 mL |
| 0.5 mM | 5.25 mL | 26.23 mL | 52.45 mL |
| 1 mM | 2.62 mL | 13.11 mL | 26.23 mL |
| 5 mM | 0.52 mL | 2.62 mL | 5.25 mL |
*The above data is based on the productmolecular weight 381.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13590 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 381.3 |
| Formula | C20H25ClN2OHCl |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 925681-41-0 |
| Synonyms | Akt Inhibitor X |
| SMILES | CCN(CC)CCCCN1C2=CC=CC=C2OC3=C1C=C(C=C3)Cl.Cl |
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
MK-2206 2HCl
MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM, respectively.
Triciribine
Triciribine, also known as API-2, suppresses the phosphorylation level and kinase activity of Akt.
Triciribine phosphate (NSC-280594)
Triciribine phosphate inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3, which may result in the inhibition of A…
GSK2141795 (Uprosertib, GSK795)
Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tum…
KP372-1
KP372-1 is a synthetic small molecule AKT inhibitor.
CCT128930
CCT128930 is an ATP-competitive AKT inhibitor that is a potent, advanced lead pyrrolopyrimidine compound exhibiting selectivity for AKT over…
AT7867 2HCl
AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, resp…
AZD5363
AZD5363 is a potent inhibitor of AKT with pharmacodynamic activity in vivo, has potential to treat a range of solid and hematologic tumors …
Keywords:buy 10-DEBC HCl | 10-DEBC HCl Supplier | purchase | cost | manufacturer | order | distributor | buy 925681-41-0| 925681-41-0 Supplier | purchase 925681-41-0 | 925681-41-0 cost | 925681-41-0 manufacturer | order 925681-41-0 | 925681-41-0 distributor
Contact information
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: [email protected]
Not your Region? View all Distributors
Adooq Quality Guarantee
We promise all products perform as described.