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$0.00 Biological Activity
10-DEBC HCl is a selective inhibitor of Akt/PKB. It inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.23 mL | 131.13 mL | 262.26 mL |
| 0.5 mM | 5.25 mL | 26.23 mL | 52.45 mL |
| 1 mM | 2.62 mL | 13.11 mL | 26.23 mL |
| 5 mM | 0.52 mL | 2.62 mL | 5.25 mL |
*The above data is based on the productmolecular weight 381.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A13590 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 381.3 |
| Formula | C20H25ClN2OHCl |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 925681-41-0 |
| Synonyms | Akt Inhibitor X |
| SMILES | CCN(CC)CCCCN1C2=CC=CC=C2OC3=C1C=C(C=C3)Cl.Cl |
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