Biological Activity
12-O-tetradecanoyl phorbol-13-acetate is a diester of phorbol and is a tumor promoting compound extracted from croton oil. It is a reversible, highly potent protein kinase C (PKC) activator in vitro and in vivo at nM concentrations.
In vitro | DMSO | 94 mg/mL (152.38 mM) | |
Water | Insoluble | ||
Ethanol | 94 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 16.21 mL | 81.06 mL | 162.12 mL |
0.5 mM | 3.24 mL | 16.21 mL | 32.42 mL |
1 mM | 1.62 mL | 8.11 mL | 16.21 mL |
5 mM | 0.32 mL | 1.62 mL | 3.24 mL |
*The above data is based on the productmolecular weight 616.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A14616 |
---|---|
Actions | Activator |
CAS No. | 16561-29-8 |
Formula | C36H56O8 |
M. Wt | 616.83 |
Purity | >98% |
Synonyms | TPA, Phorbol 12-myristate 13-acetate |
SMILES | CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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