12-O-tetradecanoyl phorbol-13-acetate

12-O-tetradecanoyl phorbol-13-acetate Chemical Structure

CAS NO. 16561-29-8

12-O-tetradecanoyl phorbol-13-acetate is a diester of phorbol and is a tumor promoting compound extracted from croton oil. It is a reversible, highly potent protein kinase C (PKC) activator in vitro and in vivo at nM concentrations.

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5 mg
$105.00
10 mg
$150.00
25 mg
$270.00
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Biological Activity

12-O-tetradecanoyl phorbol-13-acetate is a diester of phorbol and is a tumor promoting compound extracted from croton oil. It is a reversible, highly potent protein kinase C (PKC) activator in vitro and in vivo at nM concentrations.
In vitro DMSO 94 mg/mL (152.38 mM)
Water Insoluble
Ethanol 94 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.21 mL 81.06 mL 162.12 mL
0.5 mM 3.24 mL 16.21 mL 32.42 mL
1 mM 1.62 mL 8.11 mL 16.21 mL
5 mM 0.32 mL 1.62 mL 3.24 mL

*The above data is based on the productmolecular weight 616.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14616
Actions Activator
CAS No. 16561-29-8
Formula C36H56O8
M. Wt 616.83
Purity >98%
Synonyms TPA, Phorbol 12-myristate 13-acetate
SMILES CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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