12-O-tetradecanoyl phorbol-13-acetate

12-O-tetradecanoyl phorbol-13-acetate is a diester of phorbol and is a tumor promoting compound extracted from croton oil. It is a reversible, highly potent protein kinase C (PKC) activator in vitro and in vivo at nM concentrations.
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Size Price Stock Qty
1mg
$45.00
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5mg
$98.00
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10mg
$152.00
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25mg
$280.00
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50mg
$480.00
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100mg
$760.00
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10mM * 1mL in DMSO
$128.00
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's 12-O-tetradecanoyl phorbol-13-acetate has been cited by 1 publications
  • Ping Li, .et al. , J Ovarian Res, 2024, Sep 17;17(1):188 PMID: 39289738
  • Biological Activity
    Discription 12-O-tetradecanoyl phorbol-13-acetate is a diester of phorbol and is a tumor promoting compound extracted from croton oil. It is a reversible, highly potent protein kinase C (PKC) activator in vitro and in vivo at nM concentrations.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A14616
    Formula C36H56O8
    Molecular Weight 616.83
    CAS Number 16561-29-8
    SMILES CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
    Synonyms TPA, Phorbol 12-myristate 13-acetate
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 94 mg/mL (152.38 mM)
    Water Insoluble
    Ethanol 94 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 16.21 mL 81.06 mL 162.12 mL
    0.5 mM 3.24 mL 16.21 mL 32.42 mL
    1 mM 1.62 mL 8.11 mL 16.21 mL
    5 mM 0.32 mL 1.62 mL 3.24 mL
    Useful Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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