13-(Benzyloxy)-13-oxotridecanoic acid

Catalog No.: A84105
PROTAC Linker
13-(Benzyloxy)-13-oxotridecanoic acid serves as a PROTAC linker, facilitating the development of targeted protein degradation molecules. This compound is integral in the synthesis of PROTACs, which harness the ubiquitin-proteasome system to selectively degrade specific proteins within cellular contexts. Its unique structural properties enable efficient conjugation to bifunctional compounds, aiding in the exploration of therapeutic strategies in cancer and other diseases.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description13-(Benzyloxy)-13-oxotridecanoic acid serves as a PROTAC linker, facilitating the development of targeted protein degradation molecules. This compound is integral in the synthesis of PROTACs, which harness the ubiquitin-proteasome system to selectively degrade specific proteins within cellular contexts. Its unique structural properties enable efficient conjugation to bifunctional compounds, aiding in the exploration of therapeutic strategies in cancer and other diseases.
Product Information
Catalog NumA84105
FormulaC20H30O4
Molecular Weight334.46
CAS Number261178-55-6
SMILESO=C(O)CCCCCCCCCCCC(=O)OCC=1C=CC=CC1
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