15(R)-15-Methyl Prostaglandin F2α is a metabolically stable analog of PGF2α targeting prostaglandin receptors. This pharmacologically inactive prodrug is designed for activation through gastric acid, where acid-catalyzed epimerization converts it into the active 15(S)-isomer. The 15(S)-isomer effectively induces luteolysis in rhesus monkeys at approximately 12 mg per animal, making this compound valuable for research in reproductive biology and prostaglandin signaling pathways.
15(R)-15-Methyl Prostaglandin F2α is a metabolically stable analog of PGF2α targeting prostaglandin receptors. This pharmacologically inactive prodrug is designed for activation through gastric acid, where acid-catalyzed epimerization converts it into the active 15(S)-isomer. The 15(S)-isomer effectively induces luteolysis in rhesus monkeys at approximately 12 mg per animal, making this compound valuable for research in reproductive biology and prostaglandin signaling pathways.
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