Fig. 1 · Structure
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15(R)-15-Methyl Prostaglandin F2α
PGF2 Analog
15(R)-15-Methyl Prostaglandin F2α is a metabolically stable analog of PGF2α targeting prostaglandin receptors. This pharmacologically inactive prodrug is designed for activation through gastric acid, where acid-catalyzed epimerization converts it into the active 15(S)-isomer. The 15(S)-isomer effectively induces luteolysis in rhesus monkeys at approximately 12 mg per animal, making this compound valuable for research in reproductive biology and prostaglandin signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 35864-81-4 |
| Applications | PGF2 Analog |
| Formula | C21H36O5 |
| Molecular Weight | 368.51 |
| Synonyms | 15(R)-Carboprost; 15(R)-15-methyl PGF2α |
| SMILES | CCCCC[C@@](C)(O)/C=C/[C@@H]1[C@H]([C@@H](O)C[C@H]1O)C/C=C\CCCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.