15(S)-Latanoprost is a potent agonist of prostaglandin receptors, exhibiting reduced activity compared to its parent compound, latanoprost. In a binding assay utilizing cat iris sphincter muscle, 15(S)-latanoprost demonstrated an IC50 value of 24 nM. Furthermore, administration of 3 μg of 15(S)-latanoprost resulted in a measurable decrease in intraocular pressure (IOP) by 1 mmHg in normotensive cynomolgus monkeys. This compound is valuable for research into ocular conditions and the modulation of intraocular pressure.
15(S)-Latanoprost is a potent agonist of prostaglandin receptors, exhibiting reduced activity compared to its parent compound, latanoprost. In a binding assay utilizing cat iris sphincter muscle, 15(S)-latanoprost demonstrated an IC50 value of 24 nM. Furthermore, administration of 3 μg of 15(S)-latanoprost resulted in a measurable decrease in intraocular pressure (IOP) by 1 mmHg in normotensive cynomolgus monkeys. This compound is valuable for research into ocular conditions and the modulation of intraocular pressure.
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