2-(2-(2-(6-Azidohexanamido)ethoxy)ethoxy)acetic acid serves as a PROTACT linker, facilitating the synthesis of P60-L3-VHL. This compound features an azide group enabling its utilization in click chemistry, specifically through the copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups, making it a versatile tool in chemical research and bioconjugation applications.
2-(2-(2-(6-Azidohexanamido)ethoxy)ethoxy)acetic acid serves as a PROTACT linker, facilitating the synthesis of P60-L3-VHL. This compound features an azide group enabling its utilization in click chemistry, specifically through the copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups, making it a versatile tool in chemical research and bioconjugation applications.
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