2-(3-(Aminomethyl)phenyl)acetic acid functions as a PROTAC linker, facilitating the development of targeted protein degraders. This compound is instrumental in synthesizing DU-14, a specific PROTAC targeting PTP1B and TC-PTP, thereby enabling precise modulation of protein levels in cellular studies. Its application in research underscores its significance in advancing therapeutic strategies through selective degradation of proteins.
2-(3-(Aminomethyl)phenyl)acetic acid functions as a PROTAC linker, facilitating the development of targeted protein degraders. This compound is instrumental in synthesizing DU-14, a specific PROTAC targeting PTP1B and TC-PTP, thereby enabling precise modulation of protein levels in cellular studies. Its application in research underscores its significance in advancing therapeutic strategies through selective degradation of proteins.
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