2',3'-Cyclic NADP disodium serves as a substrate for phosphodiesterase (PDE), particularly 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP), which is predominantly found in myelin. This compound has been utilized in coupled enzyme assays for the precise quantification of CNP activity. Additionally, 2',3'-Cyclic NADP disodium (at a concentration of 5 μM) has demonstrated the ability to enhance calcium overload-induced calcium release and mitigate calcium-induced swelling in rat brain mitochondria, making it a valuable tool in neurobiological research.
2',3'-Cyclic NADP disodium serves as a substrate for phosphodiesterase (PDE), particularly 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP), which is predominantly found in myelin. This compound has been utilized in coupled enzyme assays for the precise quantification of CNP activity. Additionally, 2',3'-Cyclic NADP disodium (at a concentration of 5 μM) has demonstrated the ability to enhance calcium overload-induced calcium release and mitigate calcium-induced swelling in rat brain mitochondria, making it a valuable tool in neurobiological research.
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