2′,3′-Dideoxy-5-ethyluridine (ddEtUrd) is an antiretroviral agent targeting HIV. It exhibits weak anti-HIV activity and has been evaluated for its ability to inhibit HIV replication in human MT4 lymphocytes. While its phosphorylation is crucial for its antiviral effect, the compound shows limited potency, and no strong relationship has been established between ddEtUrd’s affinity for human deoxythymidine kinase or deoxycytidine kinase and its overall efficacy. This reagent is of interest in HIV research for further exploring antiviral mechanisms.
2′,3′-Dideoxy-5-ethyluridine (ddEtUrd) is an antiretroviral agent targeting HIV. It exhibits weak anti-HIV activity and has been evaluated for its ability to inhibit HIV replication in human MT4 lymphocytes. While its phosphorylation is crucial for its antiviral effect, the compound shows limited potency, and no strong relationship has been established between ddEtUrd’s affinity for human deoxythymidine kinase or deoxycytidine kinase and its overall efficacy. This reagent is of interest in HIV research for further exploring antiviral mechanisms.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
