2-3-(Methoxycarbonyl)bicyclo[1.1.1pentan-1-yl]acetic acid

Catalog No.: A82146
PROTAC Linker
2-[3-(Methoxycarbonyl)bicyclo[1.1.1]pentan-1-yl]acetic acid functions as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the efficacy of targeted protein degradation by linking E3 ligases to the target proteins, allowing for precise modulation of cellular pathways. It is a valuable tool for researchers investigating the mechanisms of protein degradation and developing novel therapeutic interventions in various diseases.
Grouped product items
Size Price Stock Qty
100mg
$160.00
In stock
250mg
$310.00
In stock
500mg
$515.00
In stock
1g
$885.00
In stock
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description2-[3-(Methoxycarbonyl)bicyclo[1.1.1]pentan-1-yl]acetic acid functions as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the efficacy of targeted protein degradation by linking E3 ligases to the target proteins, allowing for precise modulation of cellular pathways. It is a valuable tool for researchers investigating the mechanisms of protein degradation and developing novel therapeutic interventions in various diseases.
Product Information
Catalog NumA82146
FormulaC9H12O4
Molecular Weight184.19
CAS Number1113001-63-0
SMILESO=C(O)CC12CC(C(=O)OC)(C1)C2
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