2-(4-(2-Aminoethyl)piperazin-1-yl)ethan-1-ol

Catalog No.: A84416
PROTAC Linker
2-(4-(2-Aminoethyl)piperazin-1-yl)ethan-1-ol serves as a linker in the development of PROTAC (Proteolysis Targeting Chimeras) molecules. This compound facilitates the conjugation of target proteins for ubiquitin-mediated degradation. It is essential for synthesizing innovative PROTACs that can enhance the specificity and efficacy of targeted protein degradation therapies in various biological research applications.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description2-(4-(2-Aminoethyl)piperazin-1-yl)ethan-1-ol serves as a linker in the development of PROTAC (Proteolysis Targeting Chimeras) molecules. This compound facilitates the conjugation of target proteins for ubiquitin-mediated degradation. It is essential for synthesizing innovative PROTACs that can enhance the specificity and efficacy of targeted protein degradation therapies in various biological research applications.
Product Information
Catalog NumA84416
FormulaC8H19N3O
Molecular Weight173.26
CAS Number20542-08-9
SMILESOCCN1CCN(CCN)CC1
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