2-AEMP (2-Aminoethyl methylphosphonate) functions as an antagonist of the GABA(A)-ρ1 receptor. It demonstrates competitive inhibition with an IC(50) value of 18 μM, which is substantially less potent than the 7 μM seen with TPMPA. Notably, 2-AEMP exhibits a higher release rate of inhibition upon termination compared to TPMPA. Additionally, this compound requires a shorter preincubation time to achieve its inhibitory effects, making it a valuable tool for research on GABA receptor modulation and related neurological studies.
2-AEMP (2-Aminoethyl methylphosphonate) functions as an antagonist of the GABA(A)-ρ1 receptor. It demonstrates competitive inhibition with an IC(50) value of 18 μM, which is substantially less potent than the 7 μM seen with TPMPA. Notably, 2-AEMP exhibits a higher release rate of inhibition upon termination compared to TPMPA. Additionally, this compound requires a shorter preincubation time to achieve its inhibitory effects, making it a valuable tool for research on GABA receptor modulation and related neurological studies.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
