2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane is a PEG-based linker designed for use in the synthesis of PROTACs, which facilitates targeted protein degradation. Its azide functionality enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. This versatile chemical is essential for researchers focusing on protein modulation and therapeutic applications involving PROTAC technology.
2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane is a PEG-based linker designed for use in the synthesis of PROTACs, which facilitates targeted protein degradation. Its azide functionality enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. This versatile chemical is essential for researchers focusing on protein modulation and therapeutic applications involving PROTAC technology.
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