2-Chloro-N-cyclopentyl-2′-C-methyladenosine is a potent and selective agonist for A1 adenosine receptors (A1AR). This compound effectively inhibits cAMP modulation in medium spiny neurons, specifically in both direct pathway (dMSNs) and indirect pathway (iMSNs) neuronal populations. Its role as an A1AR agonist makes it valuable for research into neuropharmacology and the modulation of synaptic transmission.
2-Chloro-N-cyclopentyl-2′-C-methyladenosine is a potent and selective agonist for A1 adenosine receptors (A1AR). This compound effectively inhibits cAMP modulation in medium spiny neurons, specifically in both direct pathway (dMSNs) and indirect pathway (iMSNs) neuronal populations. Its role as an A1AR agonist makes it valuable for research into neuropharmacology and the modulation of synaptic transmission.
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