2’-Deoxy-2’-fluoro-N3-(2S)-(2-amino-3-carbonyl] propyl-beta-D-arabinouridine

Catalog No.: A55386
Purine Nucleoside Analog
2’-Deoxy-2’-fluoro-N3-(2S)-(2-amino-3-carbonyl] propyl-beta-D-arabinouridine is a purine nucleoside analog that exerts its biological activity through the inhibition of DNA synthesis. This compound demonstrates significant antitumor effects, particularly against indolent lymphoid malignancies, by inducing apoptosis and disrupting nucleic acid metabolism. Its applications in cancer research make it a valuable tool for investigating therapeutic strategies and understanding the mechanistic pathways involved in tumorigenesis.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description2’-Deoxy-2’-fluoro-N3-(2S)-(2-amino-3-carbonyl] propyl-beta-D-arabinouridine is a purine nucleoside analog that exerts its biological activity through the inhibition of DNA synthesis. This compound demonstrates significant antitumor effects, particularly against indolent lymphoid malignancies, by inducing apoptosis and disrupting nucleic acid metabolism. Its applications in cancer research make it a valuable tool for investigating therapeutic strategies and understanding the mechanistic pathways involved in tumorigenesis.
Product Information
Catalog NumA55386
FormulaC13H18FN3O7
Molecular Weight347.30
CAS Number2072145-25-4
SMILESOC[C@@H]1[C@@H](O)[C@H](F)[C@H](N2C(N(C[C@H](N)CC(O)=O)C(C=C2)=O)=O)O1
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