2'-Deoxy-PTX is a derivative of Paclitaxel that functions as a microtubule assembly inducer. It binds efficiently to GMPcPP-stabilized microtubules, exhibiting a binding affinity with a Kaapp of 0.50 × 10^6 M^-1. By promoting the assembly of tubulin into stable microtubules, 2'-Deoxy-PTX serves as a valuable reagent in cancer research, particularly in studies focused on prostate cancer.
2'-Deoxy-PTX is a derivative of Paclitaxel that functions as a microtubule assembly inducer. It binds efficiently to GMPcPP-stabilized microtubules, exhibiting a binding affinity with a Kaapp of 0.50 × 10^6 M^-1. By promoting the assembly of tubulin into stable microtubules, 2'-Deoxy-PTX serves as a valuable reagent in cancer research, particularly in studies focused on prostate cancer.
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