2-tert-Butyl 6-methyl 2-azaspiro3.3heptane-2,6-dicarboxylate

Catalog No.: A80075
PROTAC Linker
2-tert-Butyl 6-methyl 2-azaspiro[3.3]heptane-2,6-dicarboxylate serves as an effective PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in enhancing the selective degradation of target proteins via the ubiquitin-proteasome system. Its structural attributes support efficient conjugation to both ligands and E3 ligases, making it a valuable tool in chemical biology and drug discovery applications.
Grouped product items
Size Price Stock Qty
100mg
$60.00
In stock
250mg
$100.00
In stock
500mg
$145.00
In stock
1g
$205.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description2-tert-Butyl 6-methyl 2-azaspiro[3.3]heptane-2,6-dicarboxylate serves as an effective PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in enhancing the selective degradation of target proteins via the ubiquitin-proteasome system. Its structural attributes support efficient conjugation to both ligands and E3 ligases, making it a valuable tool in chemical biology and drug discovery applications.
Product Information
Catalog NumA80075
FormulaC13H21NO4
Molecular Weight255.31
CAS Number1408074-81-6
SMILESO=C(OC(C)(C)C)N1CC2(C1)CC(C(=O)OC)C2
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