20:4 Lyso PI is a selective agonist of the G protein-coupled receptor GPR55, exhibiting a potency with an EC50 value of 10 nM in inducing cell rounding in GPR55-expressing HEK293 cells. This compound activates RhoA, leading to ROCK-dependent cytoskeletal rearrangement, and stimulates the ERK signaling pathway while increasing intracellular free calcium levels. 20:4 Lyso PI is valuable for research into immune diseases and related cellular signaling mechanisms.
20:4 Lyso PI is a selective agonist of the G protein-coupled receptor GPR55, exhibiting a potency with an EC50 value of 10 nM in inducing cell rounding in GPR55-expressing HEK293 cells. This compound activates RhoA, leading to ROCK-dependent cytoskeletal rearrangement, and stimulates the ERK signaling pathway while increasing intracellular free calcium levels. 20:4 Lyso PI is valuable for research into immune diseases and related cellular signaling mechanisms.
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