28-Epirapamycin

Catalog No.: A70347
Rapamycin Impurity
28-Epirapamycin is an impurity of Rapamycin, a well-characterized inhibitor of the mechanistic target of rapamycin (mTOR). It exhibits potent biological activity with an inhibitory concentration (IC50) of 0.1 nM in HEK293 cells. This compound is primarily utilized for research involving mTOR signaling pathways and cellular growth regulation. It is valuable for studies focused on cancer, metabolic disorders, and age-related diseases.
Grouped product items
Size Price Stock Qty
5mg
$365.00
In stock
10mg
$605.00
In stock
25mg
$1,210.00
In stock
50mg
$1,885.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description28-Epirapamycin is an impurity of Rapamycin, a well-characterized inhibitor of the mechanistic target of rapamycin (mTOR). It exhibits potent biological activity with an inhibitory concentration (IC50) of 0.1 nM in HEK293 cells. This compound is primarily utilized for research involving mTOR signaling pathways and cellular growth regulation. It is valuable for studies focused on cancer, metabolic disorders, and age-related diseases.
Product Information
Catalog NumA70347
FormulaC51H79NO13
Molecular Weight914.17
CAS Number253431-35-5
SMILESO=C(C([C@](O[C@]1([H])C[C@@H](/C(C)=C/C=C/C=C/[C@H]2C)OC)([C@@H](CC1)C)O)=O)N(CCCC3)[C@]3([H])C(O[C@](CC([C@@H](/C=C([C@@H]([C@H](C([C@@H](C2)C)=O)OC)O)\C)C)=O)([H])[C@H](C)C[C@H](CC[C@H]4O)C[C@H]4OC)=O
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