3-(1-((Benzyloxy)carbonyl)piperidin-4-yl)propanoic acid

Catalog No.: A84389
PROTAC Linker
3-(1-((Benzyloxy)carbonyl)piperidin-4-yl)propanoic acid is a PROTAC linker designed to facilitate the development of proteolysis-targeting chimeras (PROTACs). This compound plays a critical role in connecting targeting ligands to E3 ligase recruiters, enabling the selective degradation of specific proteins. Its application extends to drug discovery and development, particularly in the context of targeted protein degradation strategies.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description3-(1-((Benzyloxy)carbonyl)piperidin-4-yl)propanoic acid is a PROTAC linker designed to facilitate the development of proteolysis-targeting chimeras (PROTACs). This compound plays a critical role in connecting targeting ligands to E3 ligase recruiters, enabling the selective degradation of specific proteins. Its application extends to drug discovery and development, particularly in the context of targeted protein degradation strategies.
Product Information
Catalog NumA84389
FormulaC16H21NO4
Molecular Weight291.35
CAS Number63845-33-0
SMILESO=C(O)CCC1CCN(C(=O)OCC=2C=CC=CC2)CC1
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