3,3'-Dihydroxy-2,6-bis(4-hydroxybenzyl)-5-methoxybibenzyl is a potent tubulin inhibitor with an IC50 of 10 μM, effectively inhibiting tubulin polymerization. This stilbenoid compound enhances the cytotoxic effects of SN-38 in BCRP-transduced cancer cells, making it a valuable tool for cancer research. Its application is particularly relevant in the study of breast cancer, where it can help elucidate mechanisms of drug resistance and potential therapeutic strategies.
3,3'-Dihydroxy-2,6-bis(4-hydroxybenzyl)-5-methoxybibenzyl is a potent tubulin inhibitor with an IC50 of 10 μM, effectively inhibiting tubulin polymerization. This stilbenoid compound enhances the cytotoxic effects of SN-38 in BCRP-transduced cancer cells, making it a valuable tool for cancer research. Its application is particularly relevant in the study of breast cancer, where it can help elucidate mechanisms of drug resistance and potential therapeutic strategies.
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