3,4-Dibromo-Mal-PEG4-Acid is a site-specific linker designed for antibody-drug conjugates (ADCs), featuring a dibromomaleimide moiety that enables dual substitution via its two bromine atoms. The carboxylic acid group can react with primary amines in the presence of coupling agents such as EDC and HATU, facilitating the formation of stable amide bonds. Additionally, the hydrophilic PEG4 linker enhances the solubility of the resulting conjugate in aqueous environments, making it suitable for various bioconjugation applications in chemical and biological research.
3,4-Dibromo-Mal-PEG4-Acid is a site-specific linker designed for antibody-drug conjugates (ADCs), featuring a dibromomaleimide moiety that enables dual substitution via its two bromine atoms. The carboxylic acid group can react with primary amines in the presence of coupling agents such as EDC and HATU, facilitating the formation of stable amide bonds. Additionally, the hydrophilic PEG4 linker enhances the solubility of the resulting conjugate in aqueous environments, making it suitable for various bioconjugation applications in chemical and biological research.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
