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3-{4-(Dihydroxyboranyl)phenylformamido}propanoic acid

Catalog No.: A84128
PROTAC Linker
3-{[4-(Dihydroxyboranyl)phenyl]formamido}propanoic acid serves as a versatile PROTAC linker, facilitating the development of targeted protein degradation strategies. This compound plays a crucial role in synthesizing proteolysis-targeting chimeras (PROTACs), enhancing the delivery of E3 ligase-binding and target protein-binding moieties. Its unique structure allows for efficient assembly of PROTACs, making it valuable in chemical biology research and therapeutic development targeting disease-causing proteins.
3-{[4-(Dihydroxyboranyl)phenyl]formamido}propanoic acid 2024542-05-8 PROTAC Linker
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description3-{[4-(Dihydroxyboranyl)phenyl]formamido}propanoic acid serves as a versatile PROTAC linker, facilitating the development of targeted protein degradation strategies. This compound plays a crucial role in synthesizing proteolysis-targeting chimeras (PROTACs), enhancing the delivery of E3 ligase-binding and target protein-binding moieties. Its unique structure allows for efficient assembly of PROTACs, making it valuable in chemical biology research and therapeutic development targeting disease-causing proteins.
Product Information
Catalog NumA84128
FormulaC10H12BNO5
Molecular Weight237.02
CAS Number2024542-05-8
SMILESO=C(O)CCNC(=O)C1=CC=C(C=C1)B(O)O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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