3’-Azido-3’-deoxy-2-thiouridine is a purine nucleoside analog that exhibits significant anticancer activity primarily through the inhibition of DNA synthesis and the induction of apoptosis. This compound is particularly effective against indolent lymphoid malignancies, making it a valuable tool in cancer research. Additionally, it serves as a click chemistry reagent, featuring an azide group that allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules.
3’-Azido-3’-deoxy-2-thiouridine is a purine nucleoside analog that exhibits significant anticancer activity primarily through the inhibition of DNA synthesis and the induction of apoptosis. This compound is particularly effective against indolent lymphoid malignancies, making it a valuable tool in cancer research. Additionally, it serves as a click chemistry reagent, featuring an azide group that allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules.
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