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3’-Azido-3’-deoxy-5-methyl-beta-L-cytidine

Purine Nucleoside Analog

3’-Azido-3’-deoxy-5-methyl-beta-L-cytidine is a purine nucleoside analog known for its antitumor activity, particularly in indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules and can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2095417-52-8
Applications	Purine Nucleoside Analog
Formula	C₁₀H₁₄N₆O₄
Molecular Weight	282.26
SMILES	O[C@H]1[C@@H](N=[N+]=[N-])[C@H](CO)O[C@@H]1N2C=C(C)C(N)=NC2=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.