3’-Azido-3’-deoxy-5-methyl-beta-L-cytidine is a purine nucleoside analog known for its antitumor activity, particularly in indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules and can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups.
3’-Azido-3’-deoxy-5-methyl-beta-L-cytidine is a purine nucleoside analog known for its antitumor activity, particularly in indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules and can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups.
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