3’-Azido-3’-deoxy-beta-L-cytidine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its anticancer effects are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as an efficient click chemistry reagent due to its azide functional group, allowing it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It is also compatible with strain-promoted alkyne-azide cycloaddition (SPAAC) for reactions involving DBCO or BCN-modified compounds.
3’-Azido-3’-deoxy-beta-L-cytidine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its anticancer effects are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as an efficient click chemistry reagent due to its azide functional group, allowing it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It is also compatible with strain-promoted alkyne-azide cycloaddition (SPAAC) for reactions involving DBCO or BCN-modified compounds.
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