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3’-Azido-3’-deoxy-beta-L-cytidine

Purine Nucleoside Analog

3’-Azido-3’-deoxy-beta-L-cytidine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its anticancer effects are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as an efficient click chemistry reagent due to its azide functional group, allowing it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It is also compatible with strain-promoted alkyne-azide cycloaddition (SPAAC) for reactions involving DBCO or BCN-modified compounds.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2095417-59-5
Applications	Purine Nucleoside Analog
Formula	C₉H₁₂N₆O₄
Molecular Weight	268.23
SMILES	O[C@H]1[C@@H](N=[N+]=[N-])[C@H](CO)O[C@@H]1N2C=CC(N)=NC2=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.