3-O-Methylquercetin is a potent inhibitor of phosphodiesterases (PDE), targeting both cAMP and cGMP pathways with IC50 values of 13.8 μM and 14.3 μM, respectively. This compound also inhibits β-secretase with an IC50 of 6.5 μM, showcasing its potential in neuroprotective research against oxidative neuronal damage. Furthermore, 3-O-Methylquercetin exhibits significant antiviral activity against poliovirus, coxsackievirus, and human rhinovirus, along with demonstrated anti-inflammatory and trachea-relaxing properties. Its diverse biological activities make it a valuable tool for studying inflammatory diseases and respiratory conditions such as asthma.
3-O-Methylquercetin is a potent inhibitor of phosphodiesterases (PDE), targeting both cAMP and cGMP pathways with IC50 values of 13.8 μM and 14.3 μM, respectively. This compound also inhibits β-secretase with an IC50 of 6.5 μM, showcasing its potential in neuroprotective research against oxidative neuronal damage. Furthermore, 3-O-Methylquercetin exhibits significant antiviral activity against poliovirus, coxsackievirus, and human rhinovirus, along with demonstrated anti-inflammatory and trachea-relaxing properties. Its diverse biological activities make it a valuable tool for studying inflammatory diseases and respiratory conditions such as asthma.
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