Fig. 1 · Structure
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3BrB-PP1
ATP Analog
3BrB-PP1 is an ATP-competitive analog designed to selectively inhibit protein kinases with mutations in the ATP-binding pocket, particularly targeting the Thr97 mutation within Sty1. This compound offers a unique tool for investigating the effects of ATP-binding site alterations on kinase activity. Its specificity makes it valuable for studying mutant forms of kinases in various biological contexts and cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 956025-99-3 |
| Applications | ATP Analog |
| Formula | C16H18BrN5 |
| Molecular Weight | 360.25 |
| SMILES | NC1=C2C(N(C(C)(C)C)N=C2CC3=CC=CC(Br)=C3)=NC=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.