(3R,4S)-Tofacitinib is a selective JAK inhibitor, primarily targeting JAK3 with an IC50 of 1 nM. This enantiomer exhibits reduced biological activity compared to its counterpart, making it a useful tool for dissecting the role of JAK signaling in various biological processes. It is applicable in research focused on autoimmune diseases, inflammation, and related therapeutic areas.
(3R,4S)-Tofacitinib is a selective JAK inhibitor, primarily targeting JAK3 with an IC50 of 1 nM. This enantiomer exhibits reduced biological activity compared to its counterpart, making it a useful tool for dissecting the role of JAK signaling in various biological processes. It is applicable in research focused on autoimmune diseases, inflammation, and related therapeutic areas.
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