4-(2-Aminoethyl)cyclohexan-1-amine

Catalog No.: A84121
PROTAC Linker
4-(2-Aminoethyl)cyclohexan-1-amine is a versatile PROTAC linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the formation of stable covalent bonds between target proteins and E3 ligases, enabling targeted protein degradation. Its application in chemical biology research supports the development of innovative therapeutics aimed at selectively modulating protein levels in various disease contexts.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description4-(2-Aminoethyl)cyclohexan-1-amine is a versatile PROTAC linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the formation of stable covalent bonds between target proteins and E3 ligases, enabling targeted protein degradation. Its application in chemical biology research supports the development of innovative therapeutics aimed at selectively modulating protein levels in various disease contexts.
Product Information
Catalog NumA84121
FormulaC8H18N2
Molecular Weight142.25
CAS Number202256-86-8
SMILESNCCC1CCC(N)CC1
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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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