Fig. 1 · Structure
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4-Hydroxymethylpyrazole
Cat. No.
A70143
CAS
25222-43-9
Drug Metabolite
4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole, produced via hepatic oxidative metabolism. This compound exhibits a plasma concentration that correlates with the administered dosage of Fomepizole and has a relatively short half-life. It acts as an inhibitor of alcohol dehydrogenase (ADH) in humans and monkeys; however, its inhibition constant is significantly higher than that of its parent compound, suggesting a minimal in vivo impact. It is primarily used for research on metabolic pathways and drug interactions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 25222-43-9 |
| Applications | Drug Metabolite |
| Formula | C4H6N2O |
| Molecular Weight | 98.11 |
| SMILES | OCC1=CNN=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.