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4-Methylumbelliferone is a selective inhibitor of Hyaluronan (HA) synthesis which is thought to function as an inhibitor via the depletion of UDP-glucuronic acid, the common substrate for HA synthesis.
Targets
| In vitro | DMSO | 35 mg/mL (198.67 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 35 mg/mL (198.67 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 56.75 mL | 283.77 mL | 567.54 mL |
| 0.5 mM | 11.35 mL | 56.75 mL | 113.51 mL |
| 1 mM | 5.68 mL | 28.38 mL | 56.75 mL |
| 5 mM | 1.14 mL | 5.68 mL | 11.35 mL |
*The above data is based on the productmolecular weight 176.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10015 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 176.2 |
| Formula | C10H8O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 90-33-5 |
| Synonyms | 4-MU |
| SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)O |
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