(4R,5S)-Nutlin carboxylic acid-NHC2-PEG2-N3 is an E3 ligase ligand-linker conjugate designed for applications in PROTAC (proteolysis targeting chimera) technology. This compound features the (4R,5S)-Nutlin carboxylic acid, a potent MDM2 inhibitor, facilitating targeted degradation of proteins by linking to an E3 ligase. It is essential for developing PROTACs aimed at directing specific therapeutic pathways for proteins such as EZH2.
(4R,5S)-Nutlin carboxylic acid-NHC2-PEG2-N3 is an E3 ligase ligand-linker conjugate designed for applications in PROTAC (proteolysis targeting chimera) technology. This compound features the (4R,5S)-Nutlin carboxylic acid, a potent MDM2 inhibitor, facilitating targeted degradation of proteins by linking to an E3 ligase. It is essential for developing PROTACs aimed at directing specific therapeutic pathways for proteins such as EZH2.
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