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5-Azidomethyl-2’,3’,5’-tri-O-benzoyl uridine

Thymidine Analog

5-Azidomethyl-2’,3’,5’-tri-O-benzoyl uridine is a thymidine analog designed for applications in DNA research. This compound exhibits insertional activity towards replicated DNA, facilitating the labeling of cells and tracking of DNA synthesis. As a versatile click chemistry reagent, it features an azide group that engages in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, making it suitable for bioconjugation strategies involving alkyne, DBCO, or BCN functionalized molecules.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1884334-72-8
Applications	Thymidine Analog
Formula	C₃₁H₂₅N₅O₉
Molecular Weight	611.56
SMILES	O=C(NC(C(CN=[N+]=[N-])=C1)=O)N1[C@@H]2O[C@H](COC(C3=CC=CC=C3)=O)[C@@H](OC(C4=CC=CC=C4)=O)[C@H]2OC(C5=CC=CC=C5)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.