5-(Azidomethyl) arauridine is a thymidine analogue that exhibits insertional activity into replicated DNA, making it valuable for labeling and tracking DNA synthesis in cellular studies. As a click chemistry reagent, it features an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with compounds possessing DBCO or BCN groups, expanding its utility in bioconjugation applications.
5-(Azidomethyl) arauridine is a thymidine analogue that exhibits insertional activity into replicated DNA, making it valuable for labeling and tracking DNA synthesis in cellular studies. As a click chemistry reagent, it features an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with compounds possessing DBCO or BCN groups, expanding its utility in bioconjugation applications.
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