5-HT7R antagonist 4 is a selective antagonist of the 5-HT7 receptor, exhibiting a binding affinity of Ki = 2.6 nM, while demonstrating lower affinity for the 5-HT1A receptor (Ki = 476 nM). This compound serves as a valuable tool for investigating the role of 5-HT7 receptors in neurological disorders and may contribute to the development of therapeutic strategies targeting these pathways. Its pharmacological profile makes it suitable for research applications focused on serotonin-related signaling and neurodegenerative diseases.
5-HT7R antagonist 4 is a selective antagonist of the 5-HT7 receptor, exhibiting a binding affinity of Ki = 2.6 nM, while demonstrating lower affinity for the 5-HT1A receptor (Ki = 476 nM). This compound serves as a valuable tool for investigating the role of 5-HT7 receptors in neurological disorders and may contribute to the development of therapeutic strategies targeting these pathways. Its pharmacological profile makes it suitable for research applications focused on serotonin-related signaling and neurodegenerative diseases.
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