5HPP-33 is a potent inhibitor of tubulin polymerization with an IC50 of 8.1 μM. It demonstrates significant anti-proliferative activity against leukemia and multiple myeloma cells, exhibiting IC50 values ranging from 1 to 10 μM. 5HPP-33 effectively induces cell cycle arrest at the G2/M phase and promotes apoptosis, making it a valuable tool for cancer research and therapeutic studies targeting microtubule dynamics.
5HPP-33 is a potent inhibitor of tubulin polymerization with an IC50 of 8.1 μM. It demonstrates significant anti-proliferative activity against leukemia and multiple myeloma cells, exhibiting IC50 values ranging from 1 to 10 μM. 5HPP-33 effectively induces cell cycle arrest at the G2/M phase and promotes apoptosis, making it a valuable tool for cancer research and therapeutic studies targeting microtubule dynamics.
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