6-FAM-AEEAc-Stichodactyla helianthus Neurotoxin (ShK)

Catalog No.: A92275
Biochemical Assay Reagents
6-FAM-AEEAc-Stichodactyla helianthus Neurotoxin (ShK) is a fluorescent-labeled polypeptide that primarily targets voltage-gated potassium channels. This reagent exhibits potent inhibitory activity on ion channel function, making it valuable for biochemical assays focused on channel pharmacology and neurobiology. Its applications extend to studies investigating ion channel modulation and neurotoxin interactions in cellular models.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description6-FAM-AEEAc-Stichodactyla helianthus Neurotoxin (ShK) is a fluorescent-labeled polypeptide that primarily targets voltage-gated potassium channels. This reagent exhibits potent inhibitory activity on ion channel function, making it valuable for biochemical assays focused on channel pharmacology and neurobiology. Its applications extend to studies investigating ion channel modulation and neurotoxin interactions in cellular models.
Product Information
Catalog NumA92275
FormulaC196H295N55O57S7
Molecular Weight4558.23
CAS Number1927927-42-1
Sequence6-FAM-AEEAc-Arg-Ser-Cys-Ile-Asp-Thr-Ile-Pro-Lys-Ser-Arg-Cys-Thr-Ala-Phe-Gln-Cys-Lys-His-Ser-Met-Lys-Tyr-Arg-Leu-Ser-Phe-Cys-Arg-Lys-Thr-Cys-Gly-Thr-Cys (Disulfide bridge: Cys3-Cys35,Cys12-Cys28,Cys17-Cys32)
Sequence shortening6-FAM-AEEAc-RSCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC (Disulfide bridge: Cys3-Cys35,Cys12-Cys28,Cys17-Cys32)
Synonyms6-FAM-AEEAC-SHK
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