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7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine

Purine Nucleoside Analog

7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound functions as a click chemistry reagent featuring an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. This versatility makes it suitable for various applications in chemical biology and drug discovery.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2389988-54-7
Applications	Purine Nucleoside Analog
Formula	C₁₃H₁₅N₅O₅
Molecular Weight	321.29
SMILES	OC[C@@H]1C[C@@H](O)[C@H](N2C(N=C(N)NC3=O)=C3N(CC#C)C2=O)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.