Oxytocin Receptor

L-364918 is a selective antagonist of oxytocin and arginine vasopressin, exhibiting Ki values of 30 nM for oxytocin, 1300 nM for AVP-V1, and 2400 nM for AVP-V2. This compound may be beneficial for research focused on preterm labor and conditions related to water balance dysregulation. Its pharmacological profile supports investigations into the role of these neuropeptides in various physiological and pathological processes.

OT-R Agonist 1 TFA is a potent oxytocin receptor agonist with an EC50 value of 0.39 nM, making it an excellent tool for investigating oxytocin signaling pathways. Additionally, this compound exhibits V1A antagonist activity with an EC50 of 2432 nM. It is primarily utilized in research related to central nervous system disorders, providing insights into neurobiology and potential therapeutic approaches.

L-365209 is an oxytocin antagonist that selectively inhibits the binding of oxytocin to its receptors. Its primary mechanism involves blocking the physiological effects mediated by oxytocin, which is critical in processes such as social behavior, reproduction, and stress responses. This compound is valuable for research applications investigating the role of oxytocin in various physiological and pathological conditions.

OXTR modulator-1 is an oxytocin receptor (OXTR) modulator that selectively influences OXTR activity. This compound exhibits potential biological activity in enhancing social behavior and emotional processing, making it a valuable tool for research into neuropsychiatric disorders and social cognition. Its applications extend to studies investigating the physiological and therapeutic roles of oxytocin in various animal models.

OXTR modulator-2 is a selective modulator of the oxytocin receptor (OXTR), influencing pathways associated with social behavior and emotional responses. This compound enhances OXTR activity, making it instrumental in research on neuropsychiatric disorders, stress resilience, and social cognition. Its application extends to investigating the role of oxytocin in various biological processes, enabling insights into therapeutic strategies targeting mood and anxiety disorders.