Fig. 1 · Structure

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L-364918

Oxytocin/Arginine Vasopressin Antagonist

L-364918 is a selective antagonist of oxytocin and arginine vasopressin, exhibiting Ki values of 30 nM for oxytocin, 1300 nM for AVP-V1, and 2400 nM for AVP-V2. This compound may be beneficial for research focused on preterm labor and conditions related to water balance dysregulation. Its pharmacological profile supports investigations into the role of these neuropeptides in various physiological and pathological processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 122211-31-8
Applications Oxytocin/Arginine Vasopressin Antagonist
Formula C40H54N8O6
Molecular Weight 742.91
SMILES
O=C1NC(C(CC)C)C(N2NCCCC2C(N3NCCCC3C(N(C(CC4=CC=CC=C4)C(N5CCCC5C(NC1CC6=CC=CC=C6)=O)=O)C)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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