(±)9-HODE cholesteryl ester is an endogenous metabolite derived from atherogenic processes, particularly identified within atherosclerotic lesions. This compound is formed through the Cu2+-catalyzed oxidation of low-density lipoprotein (LDL) and is further metabolized by 15-lipoxygenase (15-LO) in rabbit reticulocytes and human monocytes from cholesteryl linoleate, a predominant LDL component. Its relevance in lipid metabolism and atherosclerosis research makes it a valuable reagent for studies investigating cardiovascular diseases and oxidative stress mechanisms.
(±)9-HODE cholesteryl ester is an endogenous metabolite derived from atherogenic processes, particularly identified within atherosclerotic lesions. This compound is formed through the Cu2+-catalyzed oxidation of low-density lipoprotein (LDL) and is further metabolized by 15-lipoxygenase (15-LO) in rabbit reticulocytes and human monocytes from cholesteryl linoleate, a predominant LDL component. Its relevance in lipid metabolism and atherosclerosis research makes it a valuable reagent for studies investigating cardiovascular diseases and oxidative stress mechanisms.
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