A-438079 HCl is a competitive P2X7 receptor antagonist (pIC50 = 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line). Devoid of activity at other P2 receptors (IC50 >> 10 uM).
A-438079 HCl is a competitive P2X7 receptor antagonist (pIC50 = 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line). Devoid of activity at other P2 receptors (IC50 >> 10 uM).
Product Information
Catalog Num
A12597
Formula
C13H10Cl3N5
Molecular Weight
342.608
CAS Number
899507-36-9
SMILES
ClC1=CC=CC(C2=NN=NN2CC3=CN=CC=C3)=C1Cl.Cl
Synonyms
A-438079 , A 438079, A438079, A-438079 HCl
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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