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Biological Activity
A-443654, a specific Akt inhibitor with Ki value of 160 pM, interferes with mitotic progression and bipolar spindle formation.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.16 mL | 125.79 mL | 251.57 mL |
| 0.5 mM | 5.03 mL | 25.16 mL | 50.31 mL |
| 1 mM | 2.52 mL | 12.58 mL | 25.16 mL |
| 5 mM | 0.5 mL | 2.52 mL | 5.03 mL |
*The above data is based on the productmolecular weight 397.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11287 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 552325-16-3 |
| Formula | C24H23N5O |
| M. Wt | 397.5 |
| Purity | >98% |
| Synonyms | A443654 |
| SMILES | CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OC[C@H](CC4=CNC5=CC=CC=C54)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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